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Sphingosine 1-phosphate acts as an activator for the porcine Gpr3 of constitutively active G protein-coupled receptors

✍ Scribed by Bao-le Zhang, Ye Li, Jian-hua Ding, Fu-lu Dong, Yan-jun Hou, Bao-chun Jiang, Fang-xiong Shi, Yin-xue Xu


Book ID
119923304
Publisher
SP Zhejiang University Press
Year
2012
Tongue
English
Weight
903 KB
Volume
13
Category
Article
ISSN
1673-1581

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## Abstract G‐protein‐coupled receptor 61 (GPR61) is an orphan receptor that is abundantly expressed in the brain, which suggests its involvement in various physiological functions in the central nervous system. It couples with Gs and shows constitutive activity. To investigate the role of the N‐te