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Spherical crystals of celecoxib to improve solubility, dissolution rate and micromeritic properties

โœ Scribed by Gupta, Venkadari; Mutalik, Srinivas; Patel, Madhobhai; Jani, Girish

Book ID
120275451
Publisher
Versita
Year
2007
Tongue
English
Weight
188 KB
Volume
57
Category
Article
ISSN
1330-0075

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Particle design of tolbutamide in the pr
Particle design of tolbutamide in the presence of soluble polymer or surfactant by the spherical crystallization technique: Improvement of dissolution rate
โœ A. Sano; T. Kuriki; T. Handa; H. Takeuchi; Y. Kawashima ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 436 KB ๐Ÿ‘ 1 views

Poorly soluble crystals of tolbutamide were modified in the presence of a soluble polymer or surfactant by the spherical crystallization technique, the objective being to improve the dissolution rate and to transform platelet crystals into spherical agglomerates. An HCI solution was added to a tolbu