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Microparticles-entrapped micelles: a novel delivery system to improve solubility and dissolution rate of poorly water-soluble valsartan

โœ Scribed by Parvataneni, Durga Maheswari; Devraj, Rambhau; Mangamoori, Lakshmi Narasu

Book ID
120289072
Publisher
Informa plc
Year
2013
Tongue
English
Weight
704 KB
Volume
30
Category
Article
ISSN
0265-2048

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Development of clinical dosage forms for a poorly water-soluble drug II: Formulation and characterization of a novel solid microemulsion preconcentrate system for oral delivery of a poorly water-soluble drug
โœ Ping Li; Sara R. Hynes; Thomas F. Haefele; Madhu Pudipeddi; Alan E. Royce; Abu T ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 706 KB

The solution of a poorly water-soluble drug in a liquid lipid-surfactant mixture, which served as a microemulsion preconcentrate, was converted into a solid form by incorporating it in a solid polyethylene glycol (PEG) matrix. The solid microemulsion preconcentrates thus formed consisted of Capmul P