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SPG5-related spastic paraplegia and white matter abnormalities

✍ Scribed by Marianna Ciccolella; Filippo M. Santorelli; Roberta Biancheri; Andrea Rossi


Book ID
116793904
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
121 KB
Volume
19
Category
Article
ISSN
0960-8966

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## Abstract Hereditary spastic paraplegias (HSP) are genetically and clinically heterogeneous neurodegenerative disorders. Most MR studies on HSP include very heterogeneous samples of patients, and findings were inconsistent. Here, we examined six patients with pure HSP and SPG4 mutations by clinic