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SPFH1 and SPFH2 mediate the ubiquitination and degradation of inositol 1,4,5-trisphosphate receptors in muscarinic receptor-expressing HeLa cells

✍ Scribed by Yuan Wang; Margaret M.P. Pearce; Danielle A. Sliter; James A. Olzmann; John C. Christianson; Ron R. Kopito; Stephanie Boeckmann; Christine Gagen; Gil S. Leichner; Joseph Roitelman; Richard J.H. Wojcikiewicz


Book ID
113486333
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
817 KB
Volume
1793
Category
Article
ISSN
0167-4889

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Inositol 1,4,5-trisphosphate receptor 1
✍ Bora Lee; Sook-Young Yoon; Chris Malcuit; Jan B. Parys; Rafael A. Fissore πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 330 KB

## Abstract The initiation of normal embryo development depends on the completion of all events of egg activation. In all species to date, egg activation requires an increase(s) in the intracellular concentration of calcium ([Ca^2+^]~i~), which is almost entirely mediated by inositol 1,4,5‐trisphos