The occurrence of deletions, coding sequence alterations, and intronic changes leading to aberrant splicing has been characterized among 33 spontaneous HPRTmutants in TK6 human lymphoblasts. Deletions detectable by multiplex PCR amplification accounted for 45% (15/33) of the mutant collection. Base
Spectrum of spontaneous mutations in a cDNA of the human hprt gene integrated in chromosomal DNA
β Scribed by Ikehata, Hironobu ;Akagi, Toshiaki ;Kimura, Hiroshi ;Akasaka, Susumu ;Kato, Takesi
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 964 KB
- Volume
- 219
- Category
- Article
- ISSN
- 0026-8925
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