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Spectrophotometric analysis of flavonoid-DNA interactions and DNA damaging/protecting and cytotoxic potential of flavonoids in human peripheral blood lymphocytes

✍ Scribed by Gordana Rusak; Ivo Piantanida; Lozika Mašić; Katarina Kapuralin; Ksenija Durgo; Nevenka Kopjar

Book ID
113518258
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
337 KB
Volume
188
Category
Article
ISSN
0009-2797

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In this study we have evaluated the genoprotective effect of the ethanol extract of Gymnema montanum (GLEt) leaves in human peripheral blood lymphocytes and HL-60 cell line in vitro using the comet assay. DNA damage was induced by treating the cells with H 2 O 2 and methyl methane sulphonate (MMS).