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Spectrofluorimetric determination of surface-bound thiol groups and its application to the analysis of thiol-modified silicas

✍ Scribed by Howard, A. G.; Khdary, N. H.


Book ID
121332378
Publisher
Royal Society of Chemistry
Year
2004
Tongue
English
Weight
95 KB
Volume
129
Category
Article
ISSN
0003-2654

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Using a fluorescence-based method, we have determined the number of thiol-derivatized single-stranded oligonucleotides bound to gold nanoparticles and their extent of hybridization with complementary oligonucleotides in solution. Oligonucleotide surface coverages of hexanethiol 12-mer oligonucleotid