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Spectral analysis and a closest tree method for genetic sequences

✍ Scribed by M.A. Steel; M.D. Hendy; L.A. Székely; P.L. Erdös

Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
288 KB
Volume
5
Category
Article
ISSN
0893-9659

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✦ Synopsis

We describe a new method for estimating the evolntionary tree linking a collection of species from their aligned four-state genetic sequences. This method, which can be adapted to provide a branch-and-bound algorithm, is statistically consistent provided the sequences have evolved according to a standard stochastic model of nucleotide mutation. Our approach exploits a recent group-theoretic description of this model.

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