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Spectra of BRCA1 and BRCA2 mutations in Korean patients with breast cancer: the importance of whole-gene sequencing

✍ Scribed by Jang, Ja-Hyun; Lee, Jeong Eon; Kwon, Min-Jung; Ki, Chang-Seok; Kim, Jong-Won; Nam, Seok Jin; Yang, Jung-Hyun


Book ID
119961880
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
184 KB
Volume
57
Category
Article
ISSN
1435-232X

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BRCA1 and BRCA2 germline mutations in Ko
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In order to evaluate the role of BRCA1 and BRCA2 germline mutations in Korean patients with sporadic breast cancer, 97 patients with sporadic breast cancer were analyzed for mutations in the BRCA1 and BRCA2 coding regions, by using a combination of fluorescent-conformation sensitive gel electrophore