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Specimen handling in an HPLC determination of phenylbutazone and its major metabolites in plasma, avoiding degradation of the compounds

✍ Scribed by Franssen, M. J. A. M. ;Tan, Y. ;Freij, I. ;Van Ginneken, C. A. M. ;Gribnau, F. W. J.

Book ID
105413910
Publisher
Springer
Year
1986
Tongue
Dutch
Weight
423 KB
Volume
8
Category
Article
ISSN
1573-739X

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A high-performance liquid chromatographic method using a fluorometric detector was developed for the determination of plasma concentrations of the antidepressant indalpine (I) and its major metabolite 4-[2-(3-indolyl)ethyl]-2-piperidinone (PK). the same procedure was used to measure, in urine, level