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An improved HPLC method for rapid quantitation of diazepam and its major metabolites in human plasma

✍ Scribed by Mohammad-Reza Rouini; Yalda H. Ardakani; Kambiz A. Moghaddam; F. Solatani

Book ID
116902849
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
499 KB
Volume
75
Category
Article
ISSN
0039-9140

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## Abstract A liquid chromatographic method with diode array detection (DAD) has been developed for the analysis of the antiepileptic agent lamotrigine (LTG) and its metabolites, lamotrigine 2‐__N__‐glucuronide and 2‐__N__‐methylated in plasma samples. The analytes were separated on a C8 RP column,