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Specificity of ω-conotoxin MVIIC-binding and -blocking calcium channel antibodies in Lambert-Eaton myasthenic syndrome

✍ Scribed by Yoko K. Nakao; Masakatsu Motomura; Akihito Suenaga; T. Nakamura; Toshiro Yoshimura; Mitsuhiro Tsujihata; Masataka Mori; Masao Itoh; Shigenobu Nagataki

Book ID
106095757
Publisher
Springer
Year
1999
Tongue
English
Weight
89 KB
Volume
246
Category
Article
ISSN
0340-5354

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Specificity of autoantibodies react with
Specificity of autoantibodies react with ω-conotoxin MVIIC-sensitive calcium channel in Lambert-Eaton myasthenic syndrome
✍ Akihito Suenaga; Susumu Shirabe; Tatsufumi Nakamura; Masakatsu Motomura; Mitsuhi 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 250 KB 👁 1 views

Lambert-Eaton myasthenic syndrome (LEMS) is a neurological disorder characterized by reduced presynaptic release of acetylcholine.' Antibodies measured with o-conotoxin GVIA (GVIA), a long-lasting N-type calcium channel blocker, have been detected in 44-90% of patients with LEMS and in 10-42% of pat