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Specificity of protein interactions with highly related SRC homology (SH) domains of FGR and FYN protein-tyrosine kinases

✍ Scribed by Octavio M. Rivero-Lezcano; Keith C. Robbins


Book ID
115930153
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
634 KB
Volume
338
Category
Article
ISSN
0014-5793

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Sixteen-amino-acid-long peptides, corresponding to the optimal ligand preferences of the Src homology 3 (SH3) domains of Abl, Cortactin, Crk, p53BP2, and Src, were fused to the N-terminus of Escherichia coli alkaline phosphatase (AP). These secreted fusion proteins have been used as one-step detecti