Antibody a c t i v i t y t o various histones was examined i n a s o l i d phase radioimmunoassay. More than one h a l f o f the sera from systemic lupus erythematosus (SLE) p a t i e n t s had IgM a c t i v i t y t o t o t a l histones, and a s l i g h t l y lower frequency was observed f o r IgG a
β¦ LIBER β¦
Specificity of anti-nucleoside antibodies in systemic lupus erythematosus
β Scribed by Richard H. Weisbart; Rebecca A. Garrett; Michael R. Liebling; Eugene V. Barnett; Harold E. Paulus; David H. Katz
- Book ID
- 118374209
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 641 KB
- Volume
- 27
- Category
- Article
- ISSN
- 1090-2341
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## Abstract Twentyβone sera from 11 patients with systemic lupus erythematosus were titrated with ^125^Iβssβcalf thymus DNA to determine their maximum capacity to bind DNA. Only five sera were capable of binding > 90% of the input DNA. The remaining sixteen sera showed maximum DNA binding levels be