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Specificity of anti-human CD95 (APO-1/Fas) antibodies

✍ Scribed by Ingo Schmitz; Andreas Krueger; Sven Baumann; Sabine Kirchhoff; Peter H Krammer


Book ID
117052590
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
112 KB
Volume
297
Category
Article
ISSN
0006-291X

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Mechanisms of CD95 (APO-1/Fas)-mediated
✍ Marcus E Peter; Peter H Krammer πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 English βš– 725 KB

This review covers recent advances of CD95 signaling. It focuses on CD95-interacting molecules, formation of the death inducing signaling complex and the role of caspases, particularly caspase-8, and their death substrates. We also discuss the relevance of mitochondria in the CDg5-mediated apoptotic