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Specificity in in vitro complementation of β-galactosidase from mutant M15 of E. coli

✍ Scribed by Dobrivoje V. Marinkovic; Jordan Tang

Book ID
118852445
Publisher
Elsevier Science
Year
1971
Tongue
English
Weight
322 KB
Volume
45
Category
Article
ISSN
0006-291X

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✍ Bergquist, P. L. ;Truman, Penelope 📂 Article 📅 1978 🏛 Springer 🌐 English ⚖ 304 KB

Ten out of 43 missense mutations in the lacZ gene of Escherchia coli gave rise to polypeptide chains that were degraded in vivo. While many of the mutants appeared to be fully or partially CRM-, there appeared to be no obvious correlation between degradation, map position, altered subunit associatio