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Specific T Cell Recognition of Kinetic Isomers in the Binding of Peptide to Class II Major Histocompatibility Complex

✍ Scribed by Joshua D. Rabinowitz, Michael N. Liang, Keri Tate, Christopher Lee, Craig Beeson and Harden M. McConnell


Book ID
123640774
Publisher
National Academy of Sciences
Year
1997
Tongue
English
Weight
961 KB
Volume
94
Category
Article
ISSN
0027-8424

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## Abstract The activation of helper T cells by peptides bound to proteins of the class II Major Histocompatibility Complex (MHC II) is pivotal to the initiation of an immune response. The primary functional requirement imposed on MHC II proteins is the ability to efficiently bind thousands of diff