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Localization of soluble major histocompatibility class II-peptide complexes on T cell surface

✍ Scribed by Subhashini Arimilli; Shrikant Deshpande; Bishwajit Nag

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
244 KB
Volume
50
Category
Article
ISSN
1059-910X

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## Abstract The activation of helper T cells by peptides bound to proteins of the class II Major Histocompatibility Complex (MHC II) is pivotal to the initiation of an immune response. The primary functional requirement imposed on MHC II proteins is the ability to efficiently bind thousands of diff