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Specific p53 mutations predict poor prognosis in oral squamous cell carcinoma

✍ Scribed by Yutaka Yamazaki; Itsuo Chiba; Atsuko Hirai; Chihiro Sugiura; Ken-ichi Notani; Haruhiko Kashiwazaki; Kanchu Tei; Yasunori Totsuka; Hiroshi Fukuda

Book ID
114393925
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
151 KB
Volume
39
Category
Article
ISSN
1368-8375

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✍ Shahnavaz, S. A.; Regezi, J. A.; Bradley, G.; DubοΏ½, I. D.; Jordan, R. C. K. πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 206 KB πŸ‘ 2 views

Previous studies of oral cancer have suggested that alterations of the p53 tumour suppressor gene occur early in the precancerous stage of development. However, these observations have been based on cross-sectional assessment of abnormal p53 protein staining by immunohistochemistry and may not neces