## Objective: To define the onset and duration of effect of the hla alleles that are associated with disease susceptibility and protection in juvenile rheumatoid arthritis (jra) and 2 of its subtypes. ## Methods: We typed 680 patients with jra and 254 ethnically matched unrelated controls for hla
Specific overexpression of rheumatoid arthritis–associated HLA–DR alleles and presentation of low-affinity peptides
✍ Scribed by Sophie Kerlan-Candon; Pascale Louis-Plence; Agnes Wiedemann; Bernard Combe; Jacques Clot; Jean-François Eliaou; Valérie Pinet
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 141 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective To examine the association between HLA–DRB1 alleles and the production of anti–cyclic citrullinated peptide (anti‐CCP) and rheumatoid factor (RF) autoantibodies in patients with rheumatoid arthritis (RA). ## Methods We studied 1,723 Caucasian RA patients enrolled in the
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