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Specific inhibition of human skin fibroblast chemotaxis to platelet-derived growth factor A-chain homodimer by transforming growth factor-β1

✍ Scribed by Yoshinao Soma; Masako Mizoguchi; Kenichi Yamane; Norihito Yazawa; Masahide Kubo; Hironobu Ihn; Kanako Kikuchi; Kunihiko Tamaki

Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
119 KB
Volume
293
Category
Article
ISSN
0340-3696

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Mitogenic effect of transforming growth factor β1 on human fibroblasts involves the induction of platelet-derived growth factor α receptors
✍ Osamu Ishikawa; E. Carwile LeRoy; Maria Trojanowska 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 694 KB

## Abstract Platelet‐derived growth factor (PDGF) and transforming growth factor β (TGF‐β), potent modulators of mesenchymal cell growth and differentiation, are often colocalizable in vivo. Previous in vitro studies in fibroblastic cell lines have shown variable, even antagonistic effects of TGF‐β