Specific Detection of Metastasized Human Tumor Cells in Embryonic Chicks by the Polymerase Chain Reaction
β Scribed by Endo, Yoshio ;Sasaki, Takuma ;Harada, Fumio ;Noguchi, Mika
- Book ID
- 108579119
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1990
- Tongue
- English
- Weight
- 243 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0910-5050
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
germ cells, is not a good marker for CIS and seminoma of the testis.
## BACKGROUND. The sensitive detection of circulating tumor cells and micrometastases may have important therapeutic and prognostic implications. METHODS. The molecular detection of occult tumor cells can be accomplished by amplifying tumor specific abnormalities present in the DNA or mRNA of mali
We have studied 3 I male germ cell tumors (GCTs) for probable mutations in codons 12, 13, and 6 I of HRAS, KRAS, and NRAS oncogenes using the polymerase chain reaction. Twenty of the thirty-one tumors exhibited NRAS gene mutations, 14 in codon 6 I, and six in codon 12, whereas no mutations were dete