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Species selectivity of a small molecule antagonist for the CCR1 chemokine receptor

โœ Scribed by Meina Liang; Mary Rosser; Howard P Ng; Karen May; John G Bauman; Imadul Islam; Ameen Ghannam; Peter J Kretschmer; Haifeng Pu; Laura Dunning; R.Michael Snider; Michael M Morrissey; Joseph Hesselgesser; H.Daniel Perez; Richard Horuk


Book ID
114017781
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
560 KB
Volume
389
Category
Article
ISSN
0014-2999

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Small molecule antagonists for chemokine
โœ Lianne I. Willems; Ad P. IJzerman ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 648 KB

## Abstract The chemokine receptor CCR3 is believed to play a role in the development of allergic diseases such as asthma, atopic dermatitis, and allergic rhinitis. Despite the conflicting results that have been reported regarding the importance of eosinophils and CCR3 in allergic inflammation, inh