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A dual antagonist for chemokine CCR3 receptor and histamine H1 receptor

✍ Scribed by Keiko Suzuki; Tatsuaki Morokata; Koichiro Morihira; Ippei Sato; Satoko Takizawa; Masayuki Kaneko; Koichiro Takahashi; Yasuaki Shimizu


Book ID
113586762
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
331 KB
Volume
563
Category
Article
ISSN
0014-2999

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Small molecule antagonists for chemokine
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## Abstract The chemokine receptor CCR3 is believed to play a role in the development of allergic diseases such as asthma, atopic dermatitis, and allergic rhinitis. Despite the conflicting results that have been reported regarding the importance of eosinophils and CCR3 in allergic inflammation, inh