Species differences in the rate of disappearance of fenfluramine and its effects on brain serotonin neurons
โ Scribed by Larry R. Steranka; Elaine Sanders-Bush
- Book ID
- 115774832
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 654 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0006-2952
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
This study examined the relationship between the magnitude of tissue serotonin (5-HT) depletion produced by treatment with the neurotoxin 5,7-dihydroxytryptamine (5,7-DHT) and basal and fenfluramine-induced 5-HT release in the striatum. Separate groups of rats were treated with either vehicle or 5,7
Until recently, (ฯฎ)fenfluramine (FEN) was widely prescribed as an appetite suppressant. In animals, FEN is a potent and selective brain serotonin neurotoxin. The present studies assessed the effects of phentermine (PHEN), an appetite suppressant frequently used clinically in combination with FEN, on