Recently a novel membrane-type matrix metalloproteinase-1 (MT-MMP-1) was discovered to be a specific activator of progelatinase A, and was correlated with tumor invasion. To the authors' knowledge, no information regarding the expression of MT-MMP-1 has been reported in childhood malignancies. In th
โฆ LIBER โฆ
Spatial and temporal expression profiles suggest the involvement of gelatinase A and membrane type 1 matrix metalloproteinase in amphibian metamorphosis
โ Scribed by Takashi Hasebe; Rebecca Hartman; Hiroki Matsuda; Yun-Bo Shi
- Book ID
- 106138959
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 646 KB
- Volume
- 324
- Category
- Article
- ISSN
- 0302-766X
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We have identified a novel membrane-type matrix metalloproteinase (MT-MMP) expressed on the cell surface and inducing activation of pro-gelatinase A in vitro. In this study, we further examined the possibility that MT-MMP is the activator of pro-gelatinase A in tumors as well as in vitro. Expression