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Spatial and temporal control of signaling through lipid rafts

✍ Scribed by Tamara Golub; Stefan Wacha; Pico Caroni


Book ID
113552477
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
206 KB
Volume
14
Category
Article
ISSN
0959-4388

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## Abstract Although signal pathways triggered __via__ the CD40 molecule are well characterized, those induced __via__ CD154 are less known. This study demonstrates that engagement of CD154 in Jurkat D1.1 cells with soluble CD40 leads to PKC Ξ± and Ξ΄ activation, calcium mobilization, and phosphoryla