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Role of tissue factor disulfides and lipid rafts in signaling

โœ Scribed by Usha R. Pendurthi; L. Vijaya Mohan Rao

Book ID
117257968
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
81 KB
Volume
122
Category
Article
ISSN
0049-3848

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## Abstract Although signal pathways triggered __via__ the CD40 molecule are well characterized, those induced __via__ CD154 are less known. This study demonstrates that engagement of CD154 in Jurkat D1.1 cells with soluble CD40 leads to PKC ฮฑ and ฮด activation, calcium mobilization, and phosphoryla