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Sparse Principal Component Analysis for Identifying Ancestry-Informative Markers in Genome-Wide Association Studies

✍ Scribed by Seokho Lee; Michael P. Epstein; Richard Duncan; Xihong Lin

Book ID
112095637
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
834 KB
Volume
36
Category
Article
ISSN
0741-0395

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## Abstract Many complex diseases are influenced by genetic variations in multiple genes, each with only a small marginal effect on disease susceptibility. Pathway analysis, which identifies biological pathways associated with disease outcome, has become increasingly popular for genome‐wide associa