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SOX15 is a candidate tumor suppressor in pancreatic cancer with a potential role in Wnt/β-catenin signaling

✍ Scribed by Thu, K L; Radulovich, N; Becker-Santos, D D; Pikor, L A; Pusic, A; Lockwood, W W; Lam, W L; Tsao, M-S

Book ID: 118259491
Publisher: Nature Publishing Group
Year: 2013
Tongue: English
Weight: 688 KB
Volume: 33
Category: Article
ISSN: 0950-9232
DOI: 10.1038/onc.2012.595

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## Abstract ## BACKGROUND: Abnormal activation of the Wnt/β‐catenin signaling pathway is common and critical in the pathogenesis of digestive cancers. In this study, the authors investigated the promoter methylation of the dickkopf homolog 3 gene __Dkk‐3__ in these cancers and its prognostic signi