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Sorbitol metabolism in the retina, optic nerve, and sural nerve of diabetic rats treated with an aldose reductase inhibitor

✍ Scribed by Peter Naeser; Sven E. Brolin; Ulf J. Eriksson

Book ID
118949684
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
378 KB
Volume
37
Category
Article
ISSN
1532-8600

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✍ K. R. W. Gillon; J. N. Hawthorne; D. R. Tomlinson πŸ“‚ Article πŸ“… 1983 πŸ› Springer 🌐 English βš– 756 KB

A possible relationship between increased sorbitol concentration and decreased myo-inositol concentration in peripheral nerves of diabetic rats has been examined. To this end, sorbinil, an aldose reductase inhibitor, was used either to prevent or reverse elevation of nerve sorbitol concentration in