✦ LIBER ✦

Sonographic diagnosis of thyroid nodules: Correlation with the results of sonographically guided fine-needle aspiration biopsy

✍ Scribed by Obad Kovacevic; Mirna Smetana Škurla

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 165 KB
Volume: 35
Category: Article
ISSN: 0091-2751
DOI: 10.1002/jcu.20287

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Purpose.

To assess the reliability of sonography in differentiating benign from malignant thyroid nodules and selecting lesions for fine‐needle aspiration (FNA).

Methods.

During a 2‐year period, the following 7 sonographic parameters were assessed in 129 patients with thyroid nodules: size, number, echogenicity, echotexure, margin regularity, presence of calcifications, and presence of a hypoechoic rim. Sonographically guided FNA was performed on thyroid nodules ≥5 mm in diameter. Out of 184 FNAs, we obtained 168 specimens adequate for cytologic analysis and 16 (9%) nondiagnostic specimens.

Results.

FNA diagnoses included 150 (89%) benign and 18 (11%) malignant nodules. Among 53 solitary nodules, 11 were carcinomas and 42 were benign (p < 0.01). The mean size of the carcinomas was 28 ± 12 mm versus 18 ± 10 mm for benign nodules (p < 0.01). The following sonographic features were significantly associated with malignancy: hypoechogenicity, irregular margins, calcifications, and absence of a hypoechoic rim. Differences in echotexure between malignant and benign nodules were not statistically significant.

Conclusion.

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