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Some Unusual Findings on the Carcinogenic Action of Urethane in Mice

โœ Scribed by NOBLE, R. L.; MILLAR, M. JEAN


Book ID
109557646
Publisher
Nature Publishing Group
Year
1948
Tongue
English
Weight
245 KB
Volume
162
Category
Article
ISSN
0028-0836

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The carcinogenic action and metabolism o
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Ten weekly intraperitoneal injections, starting at birth, of N-hydroxyurethane into C57BL/6 mice, produced thymic Iymphosarcomas in 44 per cent and lung adenomas in 78 per cent of survivors. Similar injections of urethane produced lymphosarcomas in 39 per cent and lung adenomas in 75 per cent of sur