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Some Substituted 3,4-Dihydropyrido [2,3-d]pyrimidines

โœ Scribed by Vanderhorst, Philip J.; Hamilton, Cliff S.


Book ID
121188617
Publisher
American Chemical Society
Year
1953
Tongue
English
Weight
284 KB
Volume
75
Category
Article
ISSN
0002-7863

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Synthesis and properties of 2-substitute
โœ L. M. Demina; M. Yu. Gavrilov; M. I. Vakhrin; M. E. Konshin ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer US ๐ŸŒ English โš– 388 KB

Cyclization of 2- (N-acetyl-N-arylamino)nicotinonitriles in the presence of dry HCI gave 1-aryl-2-methyl-4-oxo-l,4-dihydropyrido[2,3-d]pyrimidines. It was shown that they are acylated by acetic anhydride, aroyl chlorides, and phenyl isocyanate at the methyl group and that with benzaldehyde they give