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Some pharmacological effects of the ethanol extract of leaves of Annona diversifolia on the central nervous system in mice

✍ Scribed by M. E. González-Trujano; A. Navarrete; B. Reyes; E. Hong


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
90 KB
Volume
12
Category
Article
ISSN
0951-418X

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✦ Synopsis


In the present study we investigated some neuropharmacological effects of the ethanol extract of the leaves of Annona diversifolia (Annonaceae). Intraperitoneal administration of the extract delayed the onset of clonic seizures induced by pentylenetetrazole and delayed the time in the 'rota-rod' and 'swimming' test. In addition, the extract augmented the duration of sleeping time induced by sodium pentobarbital. These results indicate that the ethanol extract of the leaves of A. diversifolia has depressant activity on the central nervous system.


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