We report the effects on the central nervous system (CNS) and on analgesic activity of an aqueous extract of Cistus populifolius L. The extract was assayed for effects on spontaneous locomotor activity, methylphenidate-induced hypermotility, motor coordination, exploratory behaviour, rectal temperat
Effects of Hypericum calycinum L. Extract on the Central Nervous System in Mice
✍ Scribed by Yusuf Öztürk; Süleyman Aydin; Rana Beis; K. Hüsnü Can Başer; Hülya Berberoğlu
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 340 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0951-418X
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✦ Synopsis
Hypericum species have been used as herbal remedies for the therapy of various neurological disorders. In the present study, the efTects of Hypericum culycinum on the central nervous system were investigated using various behavioural models including swimming time, locomotor activity, tail-flick and hole-board experiments. According to the results obtained, it was found that the extract prepared from H. culycinum is as effective as the antidepressant drugs, desipramine and trimipramine, which were used for comparison with this plant extract in animal models.
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