Some methods for estimating absorption rate constant of linear one-compartment open models
โ Scribed by Barzegar-Jalali, M.
- Book ID
- 122698300
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 279 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0378-5173
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Data are mean predicted k values. Conditions: (A) nine data sets, 10% random error; (6) six data sets, 20% random error; (C) nine data sets, limited Cand t,10% random error. The real value of k for conditions A-C is 0.5. Values in parentheses are coefficients of variation; ranges are ranges of predi
The objective of this work was to develop a simple residual method to estimate the rate constant for actual or apparent zero-order absorption into a one-compartment model. The method is based on the fact that, in theory, a plot of residuals versus e 7Kt is linear for a zero-order absorption process,