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Some Cytological Effects of Griseofulvin

โœ Scribed by PAGET, G. E.; WALPOLE, A. L.


Book ID
109598859
Publisher
Nature Publishing Group
Year
1958
Tongue
English
Weight
301 KB
Volume
182
Category
Article
ISSN
0028-0836

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The genotoxic effects of griseofulvin (GF) in mouse primary spermatocytes at diakinesis metaphase I of meiosis were investigated. Griseofulvin was administered orally as a single dose of 500, 1000, 1500 and 2000 mg kg-' body wt. and a multiple treatment with a daily dose of 1009 mg kg-' body wt. for