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Some biophysical properties of the erythrocyte membrane in Duchenne muscular dystrophy

✍ Scribed by Anne Chabanel; Alfred Spiro; David Schachter; Shu Chien

Book ID
118930243
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
704 KB
Volume
76
Category
Article
ISSN
0022-510X

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## Abstract Freeze‐fracture studies of erythrocytes from patients with Duchenne muscular dystrophy revealed depletion of particles on both fracture faces of the plasma membrane. This study indicates that the structure of the erythrocyte plasma membrane is abnormal in Duchenne dystrophy and supports

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Erythrocytes from patients with Duchenne muscular dystrophy (DMD) were studied in relation to the extracellular calcium ion concentration. The shape of fresh erythrocytes in DMD was normal and not affected by Ca++. When DMD erythrocytes were stored in buffer solution with Ca++, however, the rate of