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Deformability and cell membrane properties of erythrocytes in Duchenne muscular dystrophy

✍ Scribed by Telford Conlon; Philip S. Lingard; John K. Tomkins

Book ID
115824253
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
594 KB
Volume
130
Category
Article
ISSN
0009-8981

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## Abstract Freeze‐fracture studies of erythrocytes from patients with Duchenne muscular dystrophy revealed depletion of particles on both fracture faces of the plasma membrane. This study indicates that the structure of the erythrocyte plasma membrane is abnormal in Duchenne dystrophy and supports

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Erythrocytes from patients with Duchenne muscular dystrophy (DMD) were studied in relation to the extracellular calcium ion concentration. The shape of fresh erythrocytes in DMD was normal and not affected by Ca++. When DMD erythrocytes were stored in buffer solution with Ca++, however, the rate of