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Somatic mutations of BECN1, an autophagy-related gene, in human cancers

โœ Scribed by JONG WOO LEE; EUN GOO JEONG; SUNG HAK LEE; NAM JIN YOO; SUG HYUNG LEE


Book ID
118715458
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
153 KB
Volume
115
Category
Article
ISSN
0365-5555

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Tyrosine kinases are major regulators of signal transduction cascades involved in cellular proliferation and have important roles in tumorigenesis. We have recently analyzed the tyrosine kinase gene family for alterations in human colorectal cancers and identified somatic mutations in seven members