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Somatic and germinal aneuploidy in the mouse: comparison of effects induced by vinblastine and colchicine

โœ Scribed by A. Manca; B. Bassani; B. Gustavino; P. Leopardi; A. Zijino; F. Pacchierotti


Book ID
113251871
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
174 KB
Volume
216
Category
Article
ISSN
0165-1161

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The genotoxicity of rifampicin was tested for sister chromatic exchange in bone marrow cells and for structural chromosomal aberrations in mouse germ cells. Sister chromatid exchange frequency increased after 160, 240 and 310 mg kg-' body wt. doses but not after 80 mg kg-'. In spermatocytes, 80 mg