Solvent selectivity in the resolution of some regioisomeric and diastereomeric prostaglandin intermediates on silica
✍ Scribed by M. Lõhmus; I. Kirjanen; M. Lopp; Ü. Lille
- Book ID
- 104144640
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 891 KB
- Volume
- 449
- Category
- Article
- ISSN
- 1873-3778
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✦ Synopsis
The possibilities of predicting the selectivity in the resolution of regioisomeric and diastereomeric prostaglandin intermediates on silica gel was investigated. A satisfactory correlation between log 01 and the solvent localization parameters m and m" was obtained, confirming the importance of solvent-solute localization in determining 01 values. The results will be useful in developing further the theory of the selectivity of resolution.
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