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Solvent selectivity in the resolution of some regioisomeric and diastereomeric prostaglandin intermediates on silica

✍ Scribed by M. Lõhmus; I. Kirjanen; M. Lopp; Ü. Lille


Book ID
104144640
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
891 KB
Volume
449
Category
Article
ISSN
1873-3778

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✦ Synopsis


The possibilities of predicting the selectivity in the resolution of regioisomeric and diastereomeric prostaglandin intermediates on silica gel was investigated. A satisfactory correlation between log 01 and the solvent localization parameters m and m" was obtained, confirming the importance of solvent-solute localization in determining 01 values. The results will be useful in developing further the theory of the selectivity of resolution.


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