Changes in the solvent dielectric properties are correlated with changes in polypeptide conformer populations. Gramicidin A, a peptide native to membrane environments, forms a variety of well deΓned dimeric conformations in relatively low dielectric organic solvents. However, changes in this environ
Solvent induced changes in conformation of hyaluronic acid
β Scribed by J. W. Park; B. Chakrabarti
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1977
- Tongue
- English
- Weight
- 171 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0006-3525
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Examining solute-induced changes in protein conformational equilibria is a longstanding method for probing the role of water in maintaining protein stability. Interpreting the molecular details governing the solute-induced effects, however, remains controversial. We present experimental and theoreti