Solvent-free microwave multicomponent re
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Jairo Quiroga; Carlos Cisneros; Braulio Insuasty; Rodrigo AbonΓa; Manuel Noguera
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Article
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2006
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Journal of Heterocyclic Chemistry
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English
β 112 KB
The free-solvent multicomponent reaction under microwave irradiation of 6-aminopyrimidin-4(3H)-ones (1) with dimedone (2) and N,N-dimethylformamide dimethylacetal yields the pyrimido[4,5-c]isoquinolinones (5a-j). In this process, the intermediate of cyclization was isolated. The structure of the syn