Solvent effect on ruthenium catalyzed dihydroxylation

✍ Scribed by Tony K.M. Shing; Eric K.W. Tam

• Book ID: 104260926
• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 148 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)00128-8

✦ Synopsis

The effect of different solvents on flash dihydroxylation is compared and for the first time, the replacement of ethyl acetate with acetone was shown to give a successful, cata/ytic cisdihydroxylation of the alkene moiety in cholesteryl acetate and the ruthenium catalytic cycle could be maintained by methanesulfonamide in the absence of acetonitrile.