Solvation of platinum anti-cancer drugs in methanol-water mixtures

✍ Scribed by John Burgess; Duncan N. Drasdo; Marttand S. Patel

• Publisher: Springer Netherlands
• Year: 1995
• Tongue: English
• Weight: 260 KB
• Volume: 8
• Category: Article
• ISSN: 1572-8773
• DOI: 10.1007/bf00142013

✦ Synopsis

Solubilities and transfer chemical potentials of carboplatin, cisplatin, iproplatin, and several related platinum complexes have been determined in methanol-water mixtures. The range of solvation behaviour is discussed in relation to possible oral administration of complexes of this type.