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Solution structure of the hydrophilic region of HIV-1 encoded virus protein U (Vpu) by CD and lH NMR spectroscopy

✍ Scribed by WRAY, VICTOR ;FEDERAU, TORSTEN ;HENKLEIN, PETER ;KLABUNDE, STEFAN ;KUNERT, OLAF ;SCHOMBURG, DIETMAR ;SCHUBERT, ULRICH


Book ID
115099834
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
710 KB
Volume
45
Category
Article
ISSN
0367-8377

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The peptide of 22 amino acid residues, Vpu\_P 41-62 , phosphorylated at the two sites Ser 52 and Ser 56 has been implicated in the degradation of CD4 receptor molecules, an important stage of the pathways to human immunodeficiency virus type 1 pathology (HIV-1). In order to assess the structural inf