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Solution Structure of the Head-to-Head Dimer of Calicheamicin Oligosaccharide Domain and d(CGTAGGATATCCTACG) 2

✍ Scribed by Bifulco, Giuseppe; Galeone, Aldo; Gomez-Paloma, Luigi; Nicolaou, K. C.; Chazin, Walter J.


Book ID
126076346
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
354 KB
Volume
118
Category
Article
ISSN
0002-7863

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Molecular Dynamics Docking Driven by NMR
✍ Jarrod A. Smith; Luigi Gomez-Paloma; David A. Case; Walter J. Chazin πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 906 KB

Calicheamicin yI1 is a natural product that has recently received much attention for its potent cytotoxic activity and its ability to bind and cleave duplex DNA in a sequence-specific manner. The solution structure of the calicheamicin oligosaccharide domain has been determined in complex with the D